LDH, CPK and CRP Dynamics in Professional Basketball: A Mindfulness-Music Intervention Study for Fatigue Management

Document Type : Original Article

Authors

1 Department of Sport Sciences, Faculty of Human Sciences, Shahab Danesh University of Qom, Qom, Iran

2 Department of Sport Sciences, Faculty of Letters and Humanities, University of Qom, Qom, Iran.

10.22091/arsnes.2025.13467.1030

Abstract

Objective: Professional basketball players frequently experience muscle damage and systemic inflammation due to intense physical demands. This study examines the effects of a combined mindfulness-music intervention on key biochemical markers (LDH, CPK, CRP) and fatigue management in elite athletes.
Methods: Forty male professional basketball players were randomly assigned to either an intervention group receiving 8 weeks of mindfulness training (30 min/session) combined with music therapy (20 min/session) three times weekly, or a control group maintaining regular training. Blood samples were collected at baseline, post-intervention, and 48-hours follow-up to measure LDH, CPK, and CRP levels. Psychological assessments included the Athletic Burnout Questionnaire and Perceived Stress Scale.
Results: The intervention group showed significant reductions in LDH (15.1%), CPK (18.6%), and CRP (34.4%) levels compared to controls. Psychological measures improved substantially, with 33.4% reduction in burnout scores and 35% decrease in perceived stress. Strong correlations emerged between biochemical and psychological improvements (r=0.59-0.67).
Conclusion: The mindfulness-music intervention effectively reduced muscle damage markers and inflammation while enhancing psychological recovery in professional basketball players. These findings support integrating combined psychosomatic therapies into athletic training programs for comprehensive fatigue management and performance optimization.

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